B\u011b\u017en\u00e9 pou\u017eit\u00ed
\nNolvadex je nesteroidn\u00ed antiestrogen, kter\u00fd kompetitivn\u011b inhibuje estrogenov\u00e9 receptory v c\u00edlov\u00fdch org\u00e1nech a n\u00e1dory v nich. Mechanismus jeho \u00fa\u010dinku nen\u00ed zcela prozkoum\u00e1n, i kdy\u017e je zn\u00e1mo, \u017ee se objevuje komplex Nolvadexu s receptorem a kofaktorem, kter\u00fd je n\u00e1sledn\u011b p\u0159enesen do bun\u011b\u010dn\u00e9ho j\u00e1dra, \u010d\u00edm\u017e se zabr\u00e1n\u00ed hypertrofii bun\u011bk z\u00e1visl\u00fdch na regulaci estrogenem. \u00da\u010dinek l\u00e9ku m\u016f\u017ee trvat n\u011bkolik t\u00fddn\u016f po jedn\u00e9 d\u00e1vce. Nolvadex je schopen vyvolat ovulaci u \u017een, stimulovat produkci gonadotropn\u00edch hormon\u016f hypof\u00fdzy. U mu\u017e\u016f s oligospermi\u00ed zvy\u0161uje koncentraci luteiniza\u010dn\u00edho hormonu a folikuly stimuluj\u00edc\u00edho hormonu, testosteronu a estrogenu v krevn\u00edm s\u00e9ru. Nolvadex se pou\u017e\u00edv\u00e1 k l\u00e9\u010db\u011b rakoviny prsu u \u017een a mu\u017e\u016f (zejm\u00e9na po kastraci) a tak\u00e9 p\u0159i roz\u0161\u00ed\u0159en\u00ed do jin\u00fdch \u010d\u00e1st\u00ed t\u011bla, rakoviny ledvin, melanom\u016f a sarkom\u016f m\u011bkk\u00fdch tk\u00e1n\u00ed s estrogenov\u00fdmi receptory, rakoviny vaje\u010dn\u00edk\u016f.
\nD\u00e1vkov\u00e1n\u00ed a sm\u011br
\nBerte p\u0159esn\u011b podle doporu\u010den\u00ed sv\u00e9ho l\u00e9ka\u0159e, proto\u017ee d\u00e1vkov\u00e1n\u00ed z\u00e1vis\u00ed na va\u0161em stavu. Doporu\u010duje se dlouh\u00e1 l\u00e9\u010dba (asi 2 roky). U\u017e\u00edvejte tento l\u00e9k s j\u00eddlem a velkou sklenic\u00ed vody jako jednu d\u00e1vku nebo ji rozd\u011blte na dv\u011b (u\u017e\u00edvan\u00e9 r\u00e1no a ve\u010der). Ne\u017ev\u00fdkejte je ani nedr\u0165te.
\nBezpe\u010dnostn\u00ed opat\u0159en\u00ed
\nTento l\u00e9k m\u016f\u017ee zv\u00fd\u0161it mo\u017enost vzniku rakoviny endometria. Pacientky, kter\u00e9 jsou l\u00e9\u010deny Nolvadexem, by m\u011bly b\u00fdt sledov\u00e1ny z hlediska jak\u00e9hokoli abnorm\u00e1ln\u00edho vagin\u00e1ln\u00edho krv\u00e1cen\u00ed, zm\u011bn menstrua\u010dn\u00edho cyklu, zm\u011bn vagin\u00e1ln\u00edho v\u00fdtoku nebo p\u00e1nevn\u00ed bolesti nebo tlaku.
\nKontraindikace
\nNolvadex je v rozporu u pacientek s p\u0159ecitliv\u011blost\u00ed na tento l\u00e9k a tak\u00e9 u \u017een, kter\u00e9 jsou l\u00e9\u010den\u00fdch antikoagula\u010dn\u00ed terapi\u00ed kumarinov\u00e9ho typu nebo u \u017een s hlubokou \u017eiln\u00ed tromb\u00f3zou nebo plicn\u00ed emboli\u00ed v anamn\u00e9ze, t\u011bhotn\u00fdch nebo koj\u00edc\u00edch \u017een. Opatrnosti je t\u0159eba u pacient\u016f s o\u010dn\u00edmi chorobami (v\u010detn\u011b \u0161ed\u00e9ho z\u00e1kalu), hyperlipidemi\u00ed, leukopeni\u00ed, trombocytopeni\u00ed, hyperkalc\u00e9mi\u00ed, t\u011b\u017ekou tromboflebitidou, tromboembolismem (tak\u00e9 v anamn\u00e9ze).
\nNe\u017e\u00e1douc\u00ed \u00fa\u010dinky
\nNe\u017e\u00e1douc\u00ed \u00fa\u010dinky se neo\u010dek\u00e1vaj\u00ed. Pokud se zm\u011bn\u00ed z lehk\u00fdch na z\u00e1va\u017en\u00e9, m\u011bli byste o tom okam\u017eit\u011b informovat sv\u00e9ho l\u00e9ka\u0159e. Ne\u017e\u00e1douc\u00ed \u00fa\u010dinky zp\u016fsoben\u00e9 Nolvadexem jsou: n\u00e1valy horka, nevolnost, zvracen\u00ed, p\u0159ib\u00edr\u00e1n\u00ed na v\u00e1ze, abnorm\u00e1ln\u00ed menstrua\u010dn\u00ed periody.
\nL\u00e9kov\u00e9 interakce
\nNolvadex je schopen zp\u016fsobit abnormality v jatern\u00edch a krevn\u00edch testech, proto je nutn\u00e9 pravideln\u00e9 sledov\u00e1n\u00ed ne\u017e\u00e1douc\u00edch \u00fa\u010dink\u016f zp\u016fsoben\u00fdch Nolvadexem. Pokud se objev\u00ed p\u0159\u00edznaky jako \u017eloutenka a krv\u00e1cen\u00ed, pacient by m\u011bl okam\u017eit\u011b vyhledat l\u00e9ka\u0159skou pomoc.
\nZapomenut\u00e1 d\u00e1vka
\nPokud jste zapomn\u011bli u\u017e\u00edt d\u00e1vku v\u010das, ud\u011blejte to pros\u00edm, jakmile si vzpomenete. Ale neu\u017e\u00edvejte, pokud je p\u0159\u00edli\u0161 pozd\u011b nebo je t\u00e9m\u011b\u0159 \u010das na dal\u0161\u00ed d\u00e1vku. Neu\u017e\u00edvejte dvojit\u00e9 nebo extra d\u00e1vky. U\u017eijte svou obvyklou d\u00e1vku n\u00e1sleduj\u00edc\u00ed den ve stejnou pravideln\u011b napl\u00e1novanou dobu.
\nP\u0159ed\u00e1vkov\u00e1n\u00ed
\nAkutn\u00ed p\u0159ed\u00e1vkov\u00e1n\u00ed u lid\u00ed nebylo hl\u00e1\u0161eno. U pacient\u016f s metastatick\u00fdm karcinomem l\u00e9\u010den\u00fdch maxim\u00e1ln\u011b tolerovan\u00fdmi d\u00e1vkami Nolvadexu byly pozorov\u00e1ny akutn\u00ed ne\u017e\u00e1douc\u00ed \u00fa\u010dinky projevuj\u00edc\u00ed se t\u0159esem, hyperreflexi\u00ed, nejistou ch\u016fz\u00ed a z\u00e1vrat\u011bmi. Pokud m\u00e1te podez\u0159en\u00ed, \u017ee jste u\u017eili p\u0159\u00edli\u0161 mnoho tohoto l\u00e9ku, vyhledejte okam\u017eitou l\u00e9ka\u0159skou pomoc a kontaktujte sv\u00e9ho l\u00e9ka\u0159e.
\nSkladujte
\nSkladujte p\u0159i pokojov\u00e9 teplot\u011b 20\u201325 C (68\u201377 F).
\nProhl\u00e1\u0161en\u00ed
\nPoskytujeme pouze obecn\u00e9 informace o l\u00e9ky, kter\u00fd nepokr\u00fdv\u00e1 v\u0161echny sm\u011bry, mo\u017en\u00e9 l\u00e9kov\u00e9 interakce nebo preventivn\u00ed opat\u0159en\u00ed. Informace na str\u00e1nce nelze pou\u017e\u00edt pro samol\u00e9\u010dbu a autodiagnostiku. Jak\u00e9koli konkr\u00e9tn\u00ed pokyny pro konkr\u00e9tn\u00edho pacienta by m\u011bly b\u00fdt dohodnuty se sv\u00fdm zdravotnick\u00fdm poradcem nebo l\u00e9ka\u0159em, kter\u00fd m\u00e1 na starosti dan\u00fd p\u0159\u00edpad. Odm\u00edt\u00e1me spolehlivost t\u011bchto informac\u00ed a jak\u00e9koli chyby, kter\u00e9 by mohly obsahovat. Nejsme zodpov\u011bdn\u00ed za \u017e\u00e1dn\u00e9 p\u0159\u00edm\u00e9, nep\u0159\u00edm\u00e9, zvl\u00e1\u0161tn\u00ed nebo jin\u00e9 nep\u0159\u00edm\u00e9 \u0161kody v d\u016fsledku jak\u00e9hokoli pou\u017eit\u00ed informac\u00ed na t\u011bchto str\u00e1nk\u00e1ch a tak\u00e9 za n\u00e1sledky samol\u00e9\u010dby.<\/p>\n","protected":false},"excerpt":{"rendered":"
Nolvadex Generic je schopen zp\u016fsobit ovulaci u \u017een. U mu\u017e\u016f s oligospermi\u00ed zvy\u0161uje koncentraci hormon\u016f. L\u00e9\u010dba rakoviny.<\/p>\n","protected":false},"featured_media":8734,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[591],"product_tag":[],"class_list":{"0":"post-8788","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-zdravi-zen-cs","7":"pa_active_substance-tamoxifen","9":"first","10":"instock","11":"shipping-taxable","12":"product-type-simple"},"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/www.pharmacy-content.com\/index.php?rest_route=\/wp\/v2\/product\/8788","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.pharmacy-content.com\/index.php?rest_route=\/wp\/v2\/product"}],"about":[{"href":"https:\/\/www.pharmacy-content.com\/index.php?rest_route=\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/www.pharmacy-content.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=8788"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.pharmacy-content.com\/index.php?rest_route=\/wp\/v2\/media\/8734"}],"wp:attachment":[{"href":"https:\/\/www.pharmacy-content.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=8788"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/www.pharmacy-content.com\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct_brand&post=8788"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/www.pharmacy-content.com\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct_cat&post=8788"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/www.pharmacy-content.com\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct_tag&post=8788"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}